Working Group 3

Transnational KEPs and practical collaboration

WG3 will focus on providing a set of clinical, ethical, legal and technological guidelines for consideration in a transnational KEP setup and on proposing models and optimisation algorithms for transnational KEPs. The models will consider the preferences expressed by clinicians and policy makers and will be formalised by optimisation experts during the learning procedure implemented by WG2.

A major concern is to consider rules that will promote the participation of individual countries in a transnational pool, while respecting national legal and ethical considerations and preferences. The allocation mechanism of the joint KEP should be designed in such a way that each country has an incentive to participate as required to serve the patients across the constituent countries rather than to withhold information and/or patient-donor pairs in their own national interest.

The expected increase of the KEP pool will require the study of models and optimisation methods capable of handling problems of bigger size. A discussion of optimisation techniques will have been initiated by WG2, although WG2’s focus will have been on national KEPs of typically considerably smaller size. Still, the outcomes of that discussion will be analysed by WG3, being a starting point for the studies initiated by this WG. This WG mainly requires input of optimisation experts, who will work in close dialogue with policy makers and legal/ethical scientists to guarantee fair and equitable results for all parties involved.  Emerging from this discussion will be an implementation of the software underpinning a prototype transnational KEP. This will require an IT infrastructure for data sharing, and standardisation of the data formats used in the different European countries, so database development will be crucial here.

WG3 is responsible for creating and maintaining a forum of discussion on transnational KEPs. It will analyse the medical, legal and ethical aspects that arise and must be considered when designing a fair and equitable transnational KEP and reflect those concerns on optimisation models that shall be proposed.